Prospects for the use of submicron ferrite magnetic particles in oncology

In recent years, the possibility of using magnetic nanoparticles to ensure the transfer of medicines to areas affected by malignant neoplasms has attracted much attention of researchers. Such a solution can be organized by placing the nanodose of the drug in a polymer or protein shell with the addition of ferrite nanoparticles with high values of coercive force. In this case, it becomes possible to control the release of the drug due to local heating by a magnetic field. The paper considers the possibility of obtaining nanoscale ferrite particles for inclusion in such nanocontainers and experiments on their heating by an alternating magnetic field as part of various biocompatible suspensions. Particle sizes before and after machining in a high-energy ball mill were measured using scanning electron microscopy. The resulting nanoparticles were mixed with biologically compatible liquids such as rheopolyglucine and glycerin with the addition of polyethylene glycol. The chemical composition of the suspension was confirmed by Raman spectroscopy. During the experiments, the authors measured the deposition time of ferrite particles in suspensions. The resulting magnetic fluids were placed in an alternating magnetic field to determine the possibility of their heating. The results of the experiments allow us to talk about the prospects of using this technology to create nanocontainers.